Factors predisposing to uterine infections in cows

Risk factors for the establishment of uterine bacterial disease in cattle Adapted from Sheldon and Dobson (2004).

Uterine damage

• Stillbirth, twins, dystocia, caesarean section
• Retained placenta
• Delayed uterine involution

Metabolic conditions

• Milk fever
• ketosis
• left displaced abomasum

Balance between pathogenicity and immunity

• Disruption of neutrophil function
• Type of bacterial flora in the uterine lumen
• Progesterone or glucocorticoid administration - early formation of corpus luteum
• Level of hygiene of the environment - cows or calving boxes may be less important