Mechanism of the influence of placental retention on uterine health

Cows with retained placenta exhibit higher presence of infection with E.coli (97%),
Clostridium spp.(65%) and Gram(-) anaerobes then cows without periparturient disorders

Endotoxins excreted by E. coli have a direct cytotoxic effect on cell forming
the uterine defense line impairing their function
(Zerbe et al., 2001)

The impairment of neutrophil function favours the establishment of infections with
A.pyogenes in later period
(Sheldon et al., 2000)

 


Relationship between the presence of E.coli at 1 day post partum and the prevalence of A.pyogenes and G(-) anaerobes at 14 days post partum (pp)
(Dohmen et al., 2002)

placental retention

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