
Intertocine - S
Intertocine-S (Oxytocin-S)
Intertocine-S is a synthetic oxytocin at a concentration of 10 IU per ml. There are no vasopressor or anti-diuretic fraction impurities.
Mode of action
Intertocine-S causes contractions of the smooth muscle of the oestrogen-sensitized uterus and mammary gland. It also stimulates uterine involution.
Indications
- Stimulation of uterine contractions, to facilitate parturition
- To promote the involution of the post-parturient uterus and thus aid the passage of retained placentae and removal of detritus
- To help control post-partum haemorrhage
- To promote milk let-down in cases of agalactia
Dosage and administration
Species | Dosage | Administration |
|---|---|---|
Mare | 0.5 - 5 ml (5-50 IU) | s.c. or i.m. |
Cow | 1.0 - 5 ml (10-50 IU) | s.c. or i.m. |
Sheep, Goat, Sow | 0.5 - 3 ml (5-30 IU) | s.c. or i.m. |
Bitch | 0.2 - 1 ml (2-10 IU) | s.c. or i.m. |
Queen | 0.1 - 0.5 ml (1-5 IU) | s.c. or i.m. |
The product is administered by intramuscular or subcutaneous injection: repeat if necessary after 40 minutes.
If a very quick effect is required, intravenous injection is possible. Therefore a quarter of the above mentioned dosage, diluted 1 in 10 with water for injection, is to be prepared. Inject slowly.
By any route and especially when used during parturition, low initial dosage is recommended as repeat administration is permissible.
In post-parturient animals larger doses may be employed.
Contraindications, warnings
The use of Intertocine-S is contraindicated in any form of obstructive dystocia.
When Intertocine is used as an aid to parturition, cervical dilatation must be confirmed prior to administration.
Excessive doses of Intertocine-S may delay parturition by producing incoordinated uterine contractions which interfere with the progress of the foetus, especially in multiple pregnancies.
Adrenaline reduces the effect of oxytocin on the uterus or mammary gland. For this reason the animal should not be frightened when complete oxytocin effect is desired.
Withholding period
No withholding period for meat or milk is necessary.
Storage conditions
Store at 2-8°C. Protect from light.
Presentations
Vials of 10, 25 and 50 ml, containing 10 IU Oxytocin/ml.
