Chorulon
Chorulon
Chorulon consists of the hormone human Chorionic Gonadotrophin (hCG) as a white freeze-dried crystalline powder.
Indications
Chorulon can be used for the control of fertility problems in domestic animals:
- improvement of conception rate in female animals (cattle).
- induction of ovulation in female animals (horses, dogs, cattle).
- cystic ovaries with irregular oestrous cycle, nymphomania or absence of oestrus in female animals (cattle).
- anoestrus in female animals (horses, dogs).
- delayed ovulation, prolonged oestrus in female animals (dogs).
Dosage
| Species | Indication | Dosage | Administration |
|---|---|---|---|
| Cow | Improvement of conception rate | 1500 IU at AI or mating | i.m. or i.v. |
| Heifer | Cystic ovarian disease (anoestrus, prolonged oestrus, nymphomania) | 3000 IU | i.v. |
| Delayed ovulation | |||
| Mare | Anoestrus with some follicular activity | 1500-3000 IU repeat if necessary after 2 days | i.m or i.v. |
| Induction of ovulation | 1500-3000 IU followed 24 hours later by A.I.or mating | i.v. | |
| Bitch | Anoestrus | after pre-treatment with Folligon (PMSG): 500 IU at first day of oestrus | i.m. or i.v. |
| Delayed ovulation | 100-800 IU/day | i.m. | |
| Prolonged oestrus |
Withholding period
No withholding period for meat or milk from animals treated with Chorulon is necessary. (National regulation should be observed).
Presentation
Vials of 500, 1500, 2500, 5000 and 10000 IU hCG, together with solvent for reconstitution.
Storage
Store at 8-15°C. Protect from light.
Reconstituted product should be used within 12 hours.
Contra-indications
As with all protein-containing preparations, in rare cases anaphylactoid-type reactions may occur shortly after administration. In such circumstances, prompt medication with adrenaline (1:1000) or glucocorticosteroids may be indicated.
Further information
The active compound of Chorulon is hCG, a gonadotrophin with Luteinizing Hormone (LH) activities. In the female, hCG can be used to stimulate the developing follicle towards maturation and to induce ovulation to bring about luteinization of the granulosa cells, to maintain the functional life of the corpus luteum and to increase progesterone secretion from luteinized cells. hCG also augments the action of FSH on ovarian growth.